System design for spectrally encoded video-rate near infrared tomography during magnetic resonance imaging of the breast

Brian W. Pogue; Zhiqiu Li; Colin Carpenter; Ashley Laughney; Venkataramanan Krishnaswamy; Scott C. Davis; Shudong Jiang; Keith D. Paulsen

doi:10.1117/12.778326

20 February 2008 System design for spectrally encoded video-rate near infrared tomography during magnetic resonance imaging of the breast

Brian W. Pogue, Zhiqiu Li, Colin Carpenter, Ashley Laughney, Venkataramanan Krishnaswamy, Scott C. Davis, Shudong Jiang, Keith D. Paulsen

Author Affiliations +

Proceedings Volume 6850, Multimodal Biomedical Imaging III; 68500H (2008) https://doi.org/10.1117/12.778326
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

Video rate diffuse tomography can be implemented within the magnetic resonance breast exam. The following paper outlines the basics of a spectrally encoded source set up, being designed and tested for use in breast imaging within a specialized breast surface coil. The system design maximizes input power to the breast, while confining the spectrum to a 10 nm bandwidth of near-infrared light. The center spectral band can be varied, since it is supplied by a tunable Ti:Sapphire laser. The encoding of each source is achieved by splitting the signal into individual nanometer bands through a high resolution grating, and focusing the output of this into each source fiber. This source configuration then requires spectral detection at the output, and so each detection fiber is delivered to a high resolution spectrometer to resolve the detected intensities. Breast imaging with this system has some subtle dynamic range issues, which means that light from sources farthest from the detector pickup are likely not providing useful data, but the closest 4-6 fibers near each source can provide useful data. The implementation of this is being carried out within a magnetic resonance breast array, and initial testing of the signals is shown, along with diagrams and photographs of the system configuration.

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Brian W. Pogue, Zhiqiu Li, Colin Carpenter, Ashley Laughney, Venkataramanan Krishnaswamy, Scott C. Davis, Shudong Jiang, and Keith D. Paulsen "System design for spectrally encoded video-rate near infrared tomography during magnetic resonance imaging of the breast", Proc. SPIE 6850, Multimodal Biomedical Imaging III, 68500H (20 February 2008); https://doi.org/10.1117/12.778326

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