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Proceedings Article

A novel method of using hollow-core photonic crystal fiber as a Raman biosensor

[+] Author Affiliations
Majid Naji, Altaf Khetani, Hanan Anis

Univ. of Ottawa (Canada)

Neil Lagali, Rejean Munger

Ottawa Health Research Institute and The Ottawa Hospital (Canada)

Proc. SPIE 6865, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V, 68650E (February 13, 2008); doi:10.1117/12.763158
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From Conference Volume 6865

  • Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V
  • Alexander N. Cartwright; Dan V. Nicolau
  • San Jose, CA | January 19, 2008

abstract

A new method for using a non-selectively filled hollow-core photonic crystal fiber (HC-PCF) as a sensitive Raman spectroscopy platform suitable for biosensing applications is presented. A 1550 HC-PCF was completely filled with ethanol (core and cladding holes). Using a 785nm excitation laser, the Raman spectrum of ethanol in the fiber core was obtained and compared with the equivalent Raman spectrum of an ethanolfilled cuvette. Using a relatively short 9.5cm length of HC-PCF, a Raman signal enhancement factor of 40 over a bulk solution of ethanol was observed under the same excitation conditions. The small sample volume utilized and longer interaction length provides the potential for compact, sensitive, and low-power Raman sensing of biological materials

© (2008) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Majid Naji ; Altaf Khetani ; Neil Lagali ; Rejean Munger and Hanan Anis
"A novel method of using hollow-core photonic crystal fiber as a Raman biosensor", Proc. SPIE 6865, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V, 68650E (February 13, 2008); doi:10.1117/12.763158; http://dx.doi.org/10.1117/12.763158


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