Peptide targeting of quantum dots to human breast cancer cells

Emily M. Haglund; Mary-Margaret Seale-Goldsmith; Deepika Dhawan; Jane Stewart; Jose Ramos-Vara; Christy L. Cooper; Lisa M. Reece; Timothy Husk; Donald Bergstrom; Deborah Knapp; James F. Leary

doi:10.1117/12.764107

13 March 2008 Peptide targeting of quantum dots to human breast cancer cells

Emily M. Haglund, Mary-Margaret Seale-Goldsmith, Deepika Dhawan, Jane Stewart, Jose Ramos-Vara, Christy L. Cooper, Lisa M. Reece, Timothy Husk, Donald Bergstrom, Deborah Knapp, James F. Leary

Author Affiliations +

Proceedings Volume 6866, Colloidal Quantum Dots for Biomedical Applications III; 68660S (2008) https://doi.org/10.1117/12.764107
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

Nanomedical approaches to diseases such as cancer provide great promise with respect to diagnostic and therapeutic applications. The impact of nanomedicine versus conventional therapies will be realized with regard to their specific cell targeting capabilities. Semiconductor nanoparticles have distinct advantages due to their chemical conjugation and detection characteristics. The attachment of a peptide sequence, LTVSPWY, was completed. These nanoparticles successfully targeted in vitro and in vivo systems. This technology can be utilized as a base mechanism for the construction of a multifunctional nanomedical system. Nanomedicine has great potential for impacting the treatment of specific diseases and healthcare delivery methods.

Citation Download Citation

Emily M. Haglund, Mary-Margaret Seale-Goldsmith, Deepika Dhawan, Jane Stewart, Jose Ramos-Vara, Christy L. Cooper, Lisa M. Reece, Timothy Husk, Donald Bergstrom, Deborah Knapp, and James F. Leary "Peptide targeting of quantum dots to human breast cancer cells", Proc. SPIE 6866, Colloidal Quantum Dots for Biomedical Applications III, 68660S (13 March 2008); https://doi.org/10.1117/12.764107

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