Laser-optical method of visualization the local net of tissue blood vessels and its biomedical applications

M. M. Asimov; R. M. Asimov; A. N. Rubinov

doi:10.1117/12.753264

1 August 2007 Laser-optical method of visualization the local net of tissue blood vessels and its biomedical applications

M. M. Asimov, R. M. Asimov, A. N. Rubinov

Author Affiliations +

Proceedings Volume 6734, International Conference on Lasers, Applications, and Technologies 2007: Laser Technologies for Medicine; 67340S (2007) https://doi.org/10.1117/12.753264
Event: International Conference on Lasers, Applications, and Technologies '07, 2007, Minsk, Belarus

Abstract

New approach in laser-optical diagnostic methods of cell metabolism based on visualization the local net of tissue blood vessels is proposed. Optical model of laser - tissue interaction and algorithm of mathematical calculation of optical signals is developed. Novel technology of local tissue hypoxia elimination based on laser-induced photodissosiation of oxyhemoglobin in cutaneous blood vessels is developed. Method of determination of oxygen diffusion coefficient into tissue on the base of kinetics of tissue oxygenation TcPO₂ under the laser irradiation is proposed. The results of mathematical modeling the kinetic of oxygen distribution into tissue from arterial blood are presented. The possibility of calculation and determination of the level of TcPO₂ in zones with the disturbed blood microcirculation is demonstrated. The increase of the value of oxygen release rate more than for times under the irradiation by laser light is obtained. It is shown that the efficiency of laser-induced oxygenation by means of increasing oxygen concentration in blood plasma is comparable with the method of hyperbaric oxygenation (HBO) at the same time gaining advantages in local action. Different biomedical applications of developing method are discussed.

Citation Download Citation

M. M. Asimov, R. M. Asimov, and A. N. Rubinov "Laser-optical method of visualization the local net of tissue blood vessels and its biomedical applications", Proc. SPIE 6734, International Conference on Lasers, Applications, and Technologies 2007: Laser Technologies for Medicine, 67340S (1 August 2007); https://doi.org/10.1117/12.753264

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
8 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Oxygen

Laser tissue interaction

Tissue optics

Tissues

Blood

Blood vessels

Laser applications

Show All Keywords

Keywords/Phrases

Search In:

Publication Years