This paper presents a technique for local structural health monitoring (SHM) of multiple structural connections by using multi-channel wireless impedance sensor nodes based on Imote2 platform. To achieve the objective, following approaches are implemented. Firstly, an Imote2-based multi-channel wireless impedance sensor node is designed for automated and cost-efficient impedance-based SHM of structural connections. Secondly, an interface washer associate with impedance measurements is designed to monitor bearing stress which is considered as main effect on structural connections. Finally, performances of the multi-channel wireless impedance sensor node and the interface washer are experimentally validated for a bolted connection model. A damage monitoring method using RMSD index of electro-mechanical impedance signatures is used to examine the strength of each individual bolted connection.© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.