Full Content is available to subscribers

Subscribe/Learn More  >
Proceedings Article

Elastic characterization of swine aorta by scanning acoustic microscopy at 30 MHz

[+] Author Affiliations
Christopher Blase, Jürgen Bereiter-Hahn

Johann Wolfgang Goethe-Univ. (Germany)

Amit Shelke, Tribikram Kundu

The Univ. of Arizona (USA)

Proc. SPIE 7984, Health Monitoring of Structural and Biological Systems 2011, 79840Y (March 31, 2011); doi:10.1117/12.881330
Text Size: A A A
From Conference Volume 7984

  • Health Monitoring of Structural and Biological Systems 2011
  • Tribikram Kundu
  • San Diego, California, USA | March 06, 2011

abstract

The mechanical properties of blood vessel walls are important determinants of physiology and pathology of the cardiovascular system. Acoustic imaging (B mode) is routinely used in a clinical setting to determine blood flow and wall distensibility. In this study scanning acoustic microscopy in vitro is used to determine spatially resolved tissue elastic properties. Broadband excitation of 30 MHz has been applied through scanning acoustic microscopy (SAM) for topographical imaging of swine thoracic aorta in reflection mode. Three differently treated tissue samples were investigated with SAM: a) treated with elastase to remove elastin, b) autoclaving for 5 hours to remove collagen and c) fresh controlled untreated sample as control. Experimental investigations are conducted for studying the contribution of individual protein components (elastin and collagen) to the material characteristics of the aortic wall. Conventional tensile testing has been conducted on the tissue samples to study the mechanical behavior. The mechanical properties measured by SAM and tensile testing show qualitative agreement.

© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation

Christopher Blase ; Amit Shelke ; Tribikram Kundu and Jürgen Bereiter-Hahn
"Elastic characterization of swine aorta by scanning acoustic microscopy at 30 MHz", Proc. SPIE 7984, Health Monitoring of Structural and Biological Systems 2011, 79840Y (March 31, 2011); doi:10.1117/12.881330; http://dx.doi.org/10.1117/12.881330


Access This Proceeding
Sign in or Create a personal account to Buy this proceeding ($15 for members, $18 for non-members).

Figures

Tables

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Proceeding
Sign in or Create a personal account to Buy this proceeding ($15 for members, $18 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.