Image-based investigation of hemodynamics and rupture of cerebral aneurysms of a single morphological type: terminal aneurysms

Marcelo Castro; Christopher Putman; Alessandro Radaelli; Alejandro Frangi; Juan Cebral

doi:10.1117/12.769239

12 March 2008 Image-based investigation of hemodynamics and rupture of cerebral aneurysms of a single morphological type: terminal aneurysms

Marcelo Castro, Christopher Putman, Alessandro Radaelli, Alejandro Frangi, Juan Cebral

Author Affiliations +

Proceedings Volume 6916, Medical Imaging 2008: Physiology, Function, and Structure from Medical Images; 69160K (2008) https://doi.org/10.1117/12.769239
Event: Medical Imaging, 2008, San Diego, California, United States

Abstract

In this study, the relationship between hemodynamics patterns and aneurysmal rupture was investigated in cerebral aneurysms of a single morphological type (terminal aneurysms) regardless of their location. Hemodynamics information (intra-aneurysmal velocity and pressure fields and wall shear stress distributions) was derived from image-based computational fluid dynamics models with realistic patient specific anatomies. A total of 41 patient-specific models constructed from 3D rotational angiography images were analyzed. The results suggest that high wall shear stress may be associated with aneurysm rupture and that in turn different flow splitting patterns from the parent artery to the daughter branches and the aneurysm produce different levels of wall shear stress.

Citation Download Citation

Marcelo Castro, Christopher Putman, Alessandro Radaelli, Alejandro Frangi, and Juan Cebral "Image-based investigation of hemodynamics and rupture of cerebral aneurysms of a single morphological type: terminal aneurysms", Proc. SPIE 6916, Medical Imaging 2008: Physiology, Function, and Structure from Medical Images, 69160K (12 March 2008); https://doi.org/10.1117/12.769239

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