This work focuses on an analysis of wave propagation in isogrid structures as it relates to Structural Health Monitoring (SHM) methods. Assembly, integration, and testing (AI&T) of satellite structures in preparation for launch includes significant time for testing and reworking any issues that may arise. SHM methods are being investigated as a means to validate the structure during assembly and truncate the number of tests needed to qualify the structure for the launch environment. The most promising of these SHM methods uses an active wave-based method in which an actuator propagates a Lamb wave through the structure; the Lamb wave is then received by a sensor and evaluated over time to detect structural changes. To date this method has proven effective in locating structural defects in a complex satellite panel; however, the attributes associated with the first wave arrival change significantly as the wave travels through ribs and joining features. Previous studies have been conducted in simplified ribbed structures, giving initial insight into the complex wave propagation phenomena. In this work, the study has been extended numerically to the isogrid plate case. Wave propagation was modeled using commercial finite element analysis software. The results of the analyses offer further insight into the complexities of wave propagation in isogrid structures.© (2011) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.