Development of blood extraction system for health monitoring system

Kazuyoshi Tsuchiya; Naoyuki Nakanishi; Eiji Nakamachi

doi:10.1117/12.522237

29 March 2004 Development of blood extraction system for health monitoring system

Kazuyoshi Tsuchiya, Naoyuki Nakanishi, Eiji Nakamachi

Proceedings Volume 5275, BioMEMS and Nanotechnology; (2004) https://doi.org/10.1117/12.522237
Event: Microelectronics, MEMS, and Nanotechnology, 2003, Perth, Australia

Abstract

The purpose of this research is to develop the compact human blood sampling device applied for a health monitoring system(HMS), which is called “Mobile Hospital”. The HMS consists of (1) a micro electrical pumping system for blood extraction, (2) a bio-sensor to detect and evaluate an amount of Glucose, Cholesterol and Urea in extracted blood, by using enzyme such as Glucoseoxidase (GOD), Cholesteroloxidase and Urease. The mechanical design elements of the device are bio-compatible microneedle, indentation unit using a shape memory alloy(SMA) actuator and pumping unit using a piezoelectric microactuator. The design concept is the biomimetic micromachine of female mosquito’s blood sampling mechanism. The performances of the main mechanical elements such as indentation force of the microneedle, actual stroke of the indentation unit using a SMA actuator and liquid sampling ability of the pumping unit using PZT piezoelectric microactuator were measured. The 3 mm stroke of the indentation load generated by SMA actuator was 0.8mN. The amount of imitation blood extracted by using bimorph PZT actuators was about 0.5 microliters for 10 sec. A 60-micrometer outer diameter and 25-micrometer inner diameter Titanium microneedle, which size is same as female mosquito’s labium, was produced by sputter deposition.

Citation Download Citation

Kazuyoshi Tsuchiya, Naoyuki Nakanishi, and Eiji Nakamachi "Development of blood extraction system for health monitoring system", Proc. SPIE 5275, BioMEMS and Nanotechnology, (29 March 2004); https://doi.org/10.1117/12.522237

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