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Proceedings Article

EPR study of the effect of terahertz radiation on the albumin conformation dynamics

[+] Author Affiliations
Eugenia F. Nemova, Olga P. Cherkasova, Vyacheslav I. Fedorov

Institute of Laser Physics (Russian Federation)

Proc. SPIE 7993, ICONO 2010: International Conference on Coherent and Nonlinear Optics, 799325 (January 11, 2011); doi:10.1117/12.880903
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From Conference Volume 7993

  • ICONO 2010: International Conference on Coherent and Nonlinear Optics
  • Kazan, Russian Federation | August 23, 2010

abstract

Effect of the preliminary irradiation of bovine serum albumin (BSA) in the terahertz spectral range on the conformation changes revealed with the help of EPR spectroscopy was investigated using the spin probing technique. The formation of the spin probe occurs directly in the aqueous solution of BSA from a nitrone compound (dihydropyrazine dioxide). It was shown that irradiation causes changes in the parameters of the EPR spectrum of the spin probe. An approach to linking the observed changes with the structural characteristics of reaction centres - the functional groups of amino acids comprising BSA - was outlined.

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Citation

Eugenia F. Nemova ; Olga P. Cherkasova and Vyacheslav I. Fedorov
"EPR study of the effect of terahertz radiation on the albumin conformation dynamics", Proc. SPIE 7993, ICONO 2010: International Conference on Coherent and Nonlinear Optics, 799325 (January 11, 2011); doi:10.1117/12.880903; http://dx.doi.org/10.1117/12.880903


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