Visualization of HIFU-induced lesions with thermoacoustic tomography

Xing Jin; Yuan Xu; Lihong V. Wang; Claudio I. Zanelli; Samuel M. Howard; Yuncai Fang

doi:10.1117/12.532359

12 July 2004 Visualization of HIFU-induced lesions with thermoacoustic tomography

Xing Jin, Yuan Xu, Lihong V. Wang, Claudio I. Zanelli, Samuel M. Howard, Yuncai Fang

Proceedings Volume 5320, Photons Plus Ultrasound: Imaging and Sensing; (2004) https://doi.org/10.1117/12.532359
Event: Biomedical Optics 2004, 2004, San Jose, CA, United States

Abstract

High-intensity focused ultrasound (HIFU) has proved to be an effective minimally invasive surgical technology. In this study, we focus on the visualization of HIFU-induced lesions using microwave-induced thermoacoustic tomography (TAT). TAT has high spatial resolution, comparable with ultrasound imaging, and high contrast, which is induced by differences in the microwave absorption rates between tumor tissue and normal tissue. TAT can, in addition, differentiate tumors before and after treatment. A single, spherically focused transducer operating at a center frequency of approximately 4 MHZ was used to generate the focused field. The lesion was generated in porcine muscle. A local-tomography-type reconstruction algorithm was applied to reconstruct the TAT image of the lesions. The lesion shown by gross pathology confirms the corresponding region measured by TAT.

Citation Download Citation

Xing Jin, Yuan Xu, Lihong V. Wang, Claudio I. Zanelli, Samuel M. Howard, and Yuncai Fang "Visualization of HIFU-induced lesions with thermoacoustic tomography", Proc. SPIE 5320, Photons Plus Ultrasound: Imaging and Sensing, (12 July 2004); https://doi.org/10.1117/12.532359

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available