Thickness measurement is the one of most fundamental measuring field. An optical method is developed for measuring the sheet thickness in real time. The automatic measurement strategy is studied which is used to realize intelligent measurement for thickness measurement equipment using a laser system. Base on the variations of measuring spaces, the status for laser sensor positions is built. The rule between sensor's position relation and measurement validity of difference measurement system with a pair of laser beams is studied; the optimal position adjusting aim under different thickness conditions of sheet to be measured is set up. According to this aim, the adjustment strategy in sheet thickness measurement system with laser is put forward to make the sensor at optimal positions during thickness measuring process based on the status. The method has the advantages of efficiency, precision and high-automation.© (2010) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.