Possibility of coherent control of spontaneous emission from four- and five-level systems in the laser radiation field is studied. The four-level system consists of two levels resonantly driven by laser radiation where either of levels may decay to a separate level. For such a system we show that the presence of the second decay channel may deteriorate the destructive interference occurring because of Autler-Townes effect in case of one decay channel. The five-level system represents two two-level resonantly driven systems with the upper levels decaying to a common level. For this case, the interference between the two decay channels is partially or completely destructive or constructive depending on the initial conditions and on the mutual orientation of the transition dipole moments. It is shown that population transfer takes place by the same quantum vacuum via spontaneous emission. The populations are shown to have damping oscillatory nature.© (2010) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.