Coherent backscattering and other phenomena of multiple-scattering of light have found a wide range of applications from the studies of wave diffusing in random media, in acoustics, random lasers, characterization and calibration of nano-scale materials, in magneto-optical traps to the planetary astronomy, with the observance of the opposition effect. With the high dependence on the coherent properties of light and the internal structure of the probing sample the coherent backscattering have the ability to detect morphological changes at the intra-cellular level. The technique has the potential to be so specific that it will revolutionize the currently used procedures for melanoma and pre-cancer detection. In current report a coherent backscattering experiment has been performed using a modified Michelson interferometer experimental setup with a He-Ne laser upon a phantom material.© (2010) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.