Multiphoton fluorescence and second harmonic generation microscopy of different skin states

Sung-Jan Lin; Wen Lo; Yen Sun; Shiou-Hwa Jee; Chen-Yuan Dong

doi:10.1117/12.587436

25 April 2005 Multiphoton fluorescence and second harmonic generation microscopy of different skin states

Sung-Jan Lin, Wen Lo, Yen Sun, Shiou-Hwa Jee, Chen-Yuan Dong

Proceedings Volume 5686, Photonic Therapeutics and Diagnostics; (2005) https://doi.org/10.1117/12.587436
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

In recent years, non-linear imaging techniques such as multiphoton fluorescence and harmonic generation microscopy have been successfully applied to dermatological imaging. Confocal-like image quality, enhanced depth penetration, and non-linear spectral signatures are among the main advantages of this family of techniques. In this presentation, we will focus on the applications of multiphoton microscopy to skin specimens in different physiological states. Images of normal and diseased tissue specimens will be presented and spectrally characterized. Our work has potential applications in developing multiphoton microscopy into a clinically applicable diagnostic tool.

Citation Download Citation

Sung-Jan Lin, Wen Lo, Yen Sun, Shiou-Hwa Jee, and Chen-Yuan Dong "Multiphoton fluorescence and second harmonic generation microscopy of different skin states", Proc. SPIE 5686, Photonic Therapeutics and Diagnostics, (25 April 2005); https://doi.org/10.1117/12.587436

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