Exposure time dependence of image quality in high-speed retinal in vivo Fourier-domain OCT

Robert Jozef Zawadzki; Bradley A. Bower; Mingtao Zhao; Marinko Sarunic; Sophie Laut; John S. Werner; Joseph A. Izatt

doi:10.1117/12.591660

18 April 2005 Exposure time dependence of image quality in high-speed retinal in vivo Fourier-domain OCT

Robert Jozef Zawadzki, Bradley A. Bower, Mingtao Zhao, Marinko Sarunic, Sophie Laut, John S. Werner, Joseph A. Izatt

Proceedings Volume 5688, Ophthalmic Technologies XV; (2005) https://doi.org/10.1117/12.591660
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

We built a Fourier domain optical coherence tomography (FD-OCT) system using a line scan CCD camera that allows real time data display and acquisition. This instrument is able to produce 2D B-scans as well as 3D data sets with human subjects in vivo in clinical settings. In this paper we analyze the influence of varying exposure times of the CCD detector on image quality. Sensitivity values derived from theoretical predictions have been compared with measurements (obtained with mirrors and neutral density filters placed in both interferometer arms). The results of these experiments, discussion about differences between sensitivity values, potential sources of discrepancies, and recommendations for optimal exposure times will be described in this paper. A short discussion of observed artifacts as well as possible ways to remove them is presented. The influence of relative retinal position with respect to reference mirror position will also be described.

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Robert Jozef Zawadzki, Bradley A. Bower, Mingtao Zhao, Marinko Sarunic, Sophie Laut, John S. Werner, and Joseph A. Izatt "Exposure time dependence of image quality in high-speed retinal in vivo Fourier-domain OCT", Proc. SPIE 5688, Ophthalmic Technologies XV, (18 April 2005); https://doi.org/10.1117/12.591660

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