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Proceedings Article

Spectral domain polarization-sensitive optical coherence tomography at 850 nm

[+] Author Affiliations
Barry Cense

Harvard Medical School, Wellman Ctr. for Photomedicine (USA) and Massachusetts General Hospital (USA)

Teresa C. Chen

Massachusetts Eye and Ear Infirmary (USA) and Harvard Medical School (USA)

Mircea Mujat, Chulmin Joo, Taner Akkin, B. H. Park, Mark C. Pierce, Andy Yun, Brett E. Bouma, Guillermo J. Tearney, Johannes F. de Boer

Wellman Ctr. for Photomedicine, Massachusetts General Hospital (USA) and Harvard Medical School (USA)

Proc. SPIE 5690, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX, 159 (April 19, 2005); doi:10.1117/12.592840
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From Conference Volume 5690

  • Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX
  • Valery V. Tuchin; Joseph A. Izatt; James G. Fujimoto
  • San Jose, CA | January 22, 2005

abstract

Spectral-Domain Polarization-Sensitive Optical Coherence Tomography (SD-PS-OCT) is a technique developed to measure the thickness and birefringence of the nerve fiber layer in vivo as a tool for the early diagnosis of glaucoma. A clinical SD-PS-OCT system was developed and scans were made around the optic nerve head (ONH) using ten concentric circles of increasing diameter. One healthy volunteer was imaged. Retinal nerve fiber layer thickness and birefringence information was extracted from the data. Polarization-sensitive OCT images were acquired at video rate (29 frames per second (fps), 1000 A-lines / frame) and at 7 fps (1000 A-lines / frame). The last setting improved the signal to noise ratio by approximately 6 dB. Birefringence measurements on the healthy volunteer gave similar results as earlier reported values that were obtained with a time-domain setup. The measurement time was reduced from more than a minute to less than a second.

© (2005) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Barry Cense ; Teresa C. Chen ; Mircea Mujat ; Chulmin Joo ; Taner Akkin, et al.
"Spectral domain polarization-sensitive optical coherence tomography at 850 nm", Proc. SPIE 5690, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX, 159 (April 19, 2005); doi:10.1117/12.592840; http://dx.doi.org/10.1117/12.592840


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