Effect of glucose on the optical properties of arterial blood using Mie theory simulations

Neil T. Clancy; Martin J. Leahy

doi:10.1117/12.633039

7 October 2005 Effect of glucose on the optical properties of arterial blood using Mie theory simulations

Neil T. Clancy, Martin J. Leahy

Proceedings Volume 5862, Diagnostic Optical Spectroscopy in Biomedicine III; 58620Y (2005) https://doi.org/10.1117/12.633039
Event: European Conferences on Biomedical Optics 2005, 2005, Munich, Germany

Abstract

The glucose concentration in arterial plasma has immediate effects on the optical properties of blood-bearing tissue due primarily to the alteration of refractive index mismatch between the scattering particles (red blood cells) and the medium (plasma). The influence of these effects on pulse oximetry is investigated using a numerical model based on Mie theory. The objective is to determine whether or not physiological fluctuations in blood glucose levels could sufficiently vary the optical properties to shift the calibration curve of a commercial pulse oximeter significantly.

Citation Download Citation

Neil T. Clancy and Martin J. Leahy "Effect of glucose on the optical properties of arterial blood using Mie theory simulations", Proc. SPIE 5862, Diagnostic Optical Spectroscopy in Biomedicine III, 58620Y (7 October 2005); https://doi.org/10.1117/12.633039

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