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Proceedings Article

Indocyanine green-laser thermolysis of acne vulgaris

[+] Author Affiliations
Elina A. Genina, Alexey N. Bashkatov, Georgy V. Simonenko, Valery V. Tuchin

Saratov State Univ. (Russia)

Ilya V. Yaroslavsky, Gregory B. Altshuler

Palomar Medical Technologies, Inc.

Proc. SPIE 5863, Therapeutic Laser Applications and Laser-Tissue Interactions II, 58630L (August 19, 2005); doi:10.1117/12.633088
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From Conference Volume 5863

  • Therapeutic Laser Applications and Laser-Tissue Interactions II
  • Hubert van den Bergh; Alfred Vogel
  • Munich, Germany | June 12, 2005

abstract

The near-infrared (NIR) laser radiation due to its high penetration depth is widely used in phototherapy and photothermolysis. In application to skin appendages a high selectivity of laser treatment is needed to prevent light action on surrounding tissues. Indocyanine Green (ICG) dye may provide a high selectivity of treatment due to effective ICG uploading by a target and its narrow band of considerable absorption just at the wavelength of the NIR diode laser. The goal of this study is to demonstrate the efficacy of the NIR diode laser photothermolysis in combination with topical application of ICG suggested for treatment of acne vulgaris . Two volunteers with back-located acne were enrolled. Skin sites of subjects were stained by ICG and irradiated by NIR laser-diode light (803 or 809 nm). The individual acne lesions were photothermally treated at 18 W/cm2 (803 nm, 0.5 sec) without skin surface cooling or at 200 W/cm2 (809 nm, 0.5 sec) with cooling. The results of the observations during a month after the treatment have shown that ICG stained acne inflammatory elements were destructed for light exposures of 0.5 sec.

© (2005) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Elina A. Genina ; Alexey N. Bashkatov ; Georgy V. Simonenko ; Valery V. Tuchin ; Ilya V. Yaroslavsky, et al.
"Indocyanine green-laser thermolysis of acne vulgaris ", Proc. SPIE 5863, Therapeutic Laser Applications and Laser-Tissue Interactions II, 58630L (August 19, 2005); doi:10.1117/12.633088; http://dx.doi.org/10.1117/12.633088


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