Dual-detector polarimetry for compensation of motion artifact in a glucose sensing system

Justin S. Baba; Gerard L. Cote

doi:10.1117/12.468329

23 May 2002 Dual-detector polarimetry for compensation of motion artifact in a glucose sensing system

Justin S. Baba, Gerard L. Cote

Proceedings Volume 4624, Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring II; (2002) https://doi.org/10.1117/12.468329
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States

Abstract

Much work has been done to make the optical measurement of glucose concentrations in the aqueous humor a feasible, non- invasive, alternative for the blood finger stick, method currently used by people with diabetes mellitus. Recent work has demonstrated that the time lag between blood and aqueous humor glucose levels is within five minutes but there is still work to be done in overcoming the confounding effects of changing birefringence, due to motion artifact, on the detected glucose signal during in-vivo measurements. To address this issue, we designed and implemented a dual orthogonal polarization detection system. We present promising preliminary results that indicate that this method, with some slight modifications and optimization of our system, has the potential to extract glucose concentration information from a birefringent sample in the presence of motion artifact.

Citation Download Citation

Justin S. Baba and Gerard L. Cote "Dual-detector polarimetry for compensation of motion artifact in a glucose sensing system", Proc. SPIE 4624, Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring II, (23 May 2002); https://doi.org/10.1117/12.468329

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