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Proceedings Article

Development imaging and experimental model for studying pathogenesis and treatment efficacy of postmastectomy lymphedema

[+] Author Affiliations
Ekateryna I. Galanzha

Saratov State Univ. and Saratov State Medical Univ. (Russia)

Valery V. Tuchin

Saratov State Univ. (Russia)

Anastasiya V. Solov'eva, Tatyana V. Stepanova, Gregory E. Brill

Saratov State Medical Univ. (Russia)

Vladimir P. Zharov

Univ. of Arkansas for Medical Sciences (USA)

Proc. SPIE 4624, Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring II, 123 (May 24, 2002); doi:10.1117/12.468315
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From Conference Volume 4624

  • Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring II
  • Alexander V. Priezzhev; Gerard L. Cote
  • San Jose, CA | January 19, 2002

abstract

The experimental model was created during an abdominal dissection of the rat mesentery and ligation of the collecting vein of mesentery. It was found that mesentery edema was developed for 20-30 min. Simultaneously monitoring of main the parameters of blood and lymph flow revealed significant increasing of interstitial water amount (up to 3 times), reduction of blood microcirculation, increasing of blood vessels permeability, decreasing of lymph microvessels diameter, phasics contractions, and lymph flow velocity.

© (2002) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Ekateryna I. Galanzha ; Valery V. Tuchin ; Anastasiya V. Solov'eva ; Tatyana V. Stepanova ; Gregory E. Brill, et al.
"Development imaging and experimental model for studying pathogenesis and treatment efficacy of postmastectomy lymphedema", Proc. SPIE 4624, Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring II, 123 (May 24, 2002); doi:10.1117/12.468315; http://dx.doi.org/10.1117/12.468315


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