Biomolecule-less sensors for biomolecules based on templated xerogel platforms

Zunyu Tao; Elizabeth C. Tehan; Rachel M. Bukowski; Ying Tang; Ellen L. Shughart; William G. Holthoff; Alexander N. Cartwright; Albert H. Titus; Frank V. Bright

doi:10.1117/12.629169

12 October 2005 Biomolecule-less sensors for biomolecules based on templated xerogel platforms

Zunyu Tao, Elizabeth C. Tehan, Rachel M. Bukowski, Ying Tang, Ellen L. Shughart, William G. Holthoff, Alexander N. Cartwright, Albert H. Titus, Frank V. Bright

Author Affiliations +

Proceedings Volume 5969, Photonic Applications in Biosensing and Imaging; 59690F (2005) https://doi.org/10.1117/12.629169
Event: Photonics North, 2005, Toronto, Canada

Abstract

We report on a new strategy for producing self-contained sensor elements for protein detection. The method exploits molecular imprinting, sol-gel-derived xerogels, and selective installation of the fluorescent reporter molecule within the template site. There are no biological reagents used. We term these new xerogel-based sensor elements as Protein Imprinted Xerogels with Integrated Emission Sites (PIXIES). The analytical figures of merit are described.

Citation Download Citation

Zunyu Tao, Elizabeth C. Tehan, Rachel M. Bukowski, Ying Tang, Ellen L. Shughart, William G. Holthoff, Alexander N. Cartwright, Albert H. Titus, and Frank V. Bright "Biomolecule-less sensors for biomolecules based on templated xerogel platforms", Proc. SPIE 5969, Photonic Applications in Biosensing and Imaging, 59690F (12 October 2005); https://doi.org/10.1117/12.629169

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available