Registration of ophthalmic images using control points

Conor Heneghan; Paul Maguire

doi:10.1117/12.463688

19 March 2003 Registration of opthalmic images using control points

Conor Heneghan, Paul Maguire

Proceedings Volume 4877, Opto-Ireland 2002: Optical Metrology, Imaging, and Machine Vision; (2003) https://doi.org/10.1117/12.463688
Event: OPTO Ireland, 2002, Galway, Ireland

Abstract

A method for registering pairs of digital ophthalmic images of the retina is presented using anatomical features as control points present in both images. The anatomical features chosen are blood vessel crossings and bifurcations. These control points are identified by a combination of local contrast enhancement, and morphological processing. In general, the matching between control points is unknown, however, so an automated algorithm is used to determine the matching pairs of control points in the two images as follows. Using two control points from each image, rigid global transform (RGT) coefficients are calculated for all possible combinations of control point pairs, and the set of RGT coefficients is identified. Once control point pairs are established, registration of two images can be achieved by using linear regression to optimize an RGT, bilinear or second order polynomial global transform. An example of cross-modal image registration using an optical image and a fluorescein angiogram of an eye is presented to illustrate the technique.

Citation Download Citation

Conor Heneghan and Paul Maguire "Registration of opthalmic images using control points", Proc. SPIE 4877, Opto-Ireland 2002: Optical Metrology, Imaging, and Machine Vision, (19 March 2003); https://doi.org/10.1117/12.463688

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