Material-specific imaging of atherosclerotic plaque using coherently scattered x rays

Melanie Therese Marie Davidson; Deidre L. Batchelar; Ian A. Cunningham

doi:10.1117/12.465617

3 May 2002 Material-specific imaging of atherosclerotic plaque using coherently scattered x rays

Melanie Therese Marie Davidson, Deidre L. Batchelar, Ian A. Cunningham

Proceedings Volume 4682, Medical Imaging 2002: Physics of Medical Imaging; (2002) https://doi.org/10.1117/12.465617
Event: Medical Imaging 2002, 2002, San Diego, California, United States

Abstract

The formation and development of plaques in the arterial wall is a direct consequence of atherosclerosis. The composition of a plaque is of particular interest as it is thought to be an important indicator of vulnerability, or risk of rupture and thrombosis. Current diagnostic methods do not yet have the ability to fully characterize plaque composition. Coherent-scatter imaging, a technique being developed in our laboratory, produces images based on the low-angle scattering properties of tissue. As these properties depend on molecular structure, material-specific maps of the different components in a tissue can be created. Material-specific images were produced for an atherosclerotic carotid artery. The image distributions of fatty and calcified deposits agreed with visual examination of the specimen. Preliminary results indicate that fat and calcifications, two typical plaque constituents, can be identified and distinguished from the undiseased vessel wall using coherently scattered x rays.

Citation Download Citation

Melanie Therese Marie Davidson, Deidre L. Batchelar, and Ian A. Cunningham "Material-specific imaging of atherosclerotic plaque using coherently scattered x rays", Proc. SPIE 4682, Medical Imaging 2002: Physics of Medical Imaging, (3 May 2002); https://doi.org/10.1117/12.465617

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