Optical characteristics of biomembrane in the development of a biosensor

J. C. Dutta; T. K. Basak; S. K. Ghosh

doi:10.1117/12.441345

25 September 2001 Optical characteristics of biomembrane in the development of a biosensor

J. C. Dutta, T. K. Basak, S. K. Ghosh

Proceedings Volume 4417, Photonics 2000: International Conference on Fiber Optics and Photonics; (2001) https://doi.org/10.1117/12.441345
Event: Photonics 2000: International Conference on Fiber Optics and Photonics, 2001, Calcutta, India

Abstract

In the work we consider certain optical properties of bio- membrane due to dichroism of polypeptides associated with membrane structures, shifting of polarization due to (pi) - electron transitions in the peptide groups and photo-induced changes in channels through which solute molecules pass. In respect of these optical characteristics, we have designed an optical fiber extrinsic sensor for measurement of permeability, particularly the Na and K diffusion through bio-membrane, based on the principle of attenuation of laser beam due to change in refractive index gradient of a liquid, induced by the variation of concentration gradient across the membrane.

Citation Download Citation

J. C. Dutta, T. K. Basak, and S. K. Ghosh "Optical characteristics of biomembrane in the development of a biosensor", Proc. SPIE 4417, Photonics 2000: International Conference on Fiber Optics and Photonics, (25 September 2001); https://doi.org/10.1117/12.441345

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