Application of I&Q detection system in scouting the curative effect of neck squamous cell carcinoma

Jun Zhang; Tao Tu; Ulas Sunar; Xavier Intes; Shoko Nioka; Zhihong Zhang; Alex Kilger; Robert A. Lustig; Laurie A. Loevner; Britton Chance

doi:10.1117/12.478177

29 July 2003 Application of I&Q detection system in scouting the curative effect of neck squamous cell carcinoma

Jun Zhang, Tao Tu, Ulas Sunar, Xavier Intes, Shoko Nioka, Zhihong Zhang, Alex Kilger, Robert A. Lustig, Laurie A. Loevner, Britton Chance

Author Affiliations +

Proceedings Volume 4955, Optical Tomography and Spectroscopy of Tissue V; (2003) https://doi.org/10.1117/12.478177
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

Near Infrared Spectroscopy (NIRS) has been widely used in cancer imaging spectroscopy because cancer tissue has more blood volume and less oxygen than normal tissue. The neck squamous cell carcinoma is ideal for our study because it’s a surface mass can be easily feel through the skin. We use a simple homodyne phase modulation system, In-phase and Quadrature Phase (I&Q) Detection system, to study the curative effect of therapy in neck cancer patients. Clinical treatment includes mainly chemical and radiation therapy, both of which alter the blood volume and the oxygenation saturation in cancer tissue. The I&Q detection system is capable of the quantification measurement of those biological changes. In this paper, we will simply introduce the I&Q detection system’s principle and constitution, and mainly explain the analysis of patients’ data.

Citation Download Citation

Jun Zhang, Tao Tu, Ulas Sunar, Xavier Intes, Shoko Nioka, Zhihong Zhang, Alex Kilger, Robert A. Lustig, Laurie A. Loevner, and Britton Chance "Application of I&Q detection system in scouting the curative effect of neck squamous cell carcinoma", Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); https://doi.org/10.1117/12.478177

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available