Monte Carlo analysis of time-resolved spatial sensitivity profiles in realistic head models

Shuhei Eda; Eiji Okada

doi:10.1117/12.434518

29 June 2001 Monte Carlo analysis of time-resolved spatial sensitivity profiles in realistic head models

Shuhei Eda, Eiji Okada

Proceedings Volume 4250, Optical Tomography and Spectroscopy of Tissue IV; (2001) https://doi.org/10.1117/12.434518
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

Time-resolved measurement enables one to restrict the volume of tissue sampled by NIRS instrument. The light propagation in the real head is more complicated, especially early detected photons are affected by the presence of low scattering cerebrospinal fluid surrounding the brain. In this study, time-resolved spatial sensitivity profiles in the realistic adult and neonatal head models are predicted by Monte Carlo simulation. The geometry of the head models is based upon the MRI scan of the adult and neonatal heads. The photon propagation is predicted by the delta-scattering technique of Monte Carlo simulation. The time-resolved spatial sensitivity profiles in the adult head are strongly affected by the low scattering CSF layer while the effect of the CSF in the neonatal head model is less significant than that in the adult head model.

Citation Download Citation

Shuhei Eda and Eiji Okada "Monte Carlo analysis of time-resolved spatial sensitivity profiles in realistic head models", Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); https://doi.org/10.1117/12.434518

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