Ultrasound-assisted NIR imaging for breast cancer detection

Nanguang Chen; Puyun Guo; Shikui Yan; Daqing Piao; Quing Zhu

doi:10.1117/12.434530

29 June 2001 Ultrasound-assisted NIR imaging for breast cancer detection

Nanguang Chen, Puyun Guo, Shikui Yan, Daqing Piao, Quing Zhu

Proceedings Volume 4250, Optical Tomography and Spectroscopy of Tissue IV; (2001) https://doi.org/10.1117/12.434530
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

We have constructed a nearly real-time combined imager suitable for simultaneous ultrasound and near infrared (NIR) diffusive light imaging and co-registration. The imager consists of a combined probe and associated electronics for data acquisition. A 2D ultrasound array occupies the center of the combined probe, while 12 dual wavelength laser source fibers (780 nm and 830 nm) and 8 optical detector fibers are deployed in the periphery. We have experimentally evaluated the effects of missing optical sensors in the middle of the combined probe upon the accuracy of the reconstructed optical absorption coefficient, and assessed the improvements of reconstructed absorption coefficient with the guidance of the co-registered ultrasound. The results have shown that when the central ultrasound array area is in the neighborhood of 2 X 2 cm², which corresponds to the size of most commercial ultrasound transducers, the quality of optical images will not be degenerated. In addition to the acoustic information for cancer discrimination, NIR image reconstruction becomes much easier and more reliable. According to our results, the iterative inversion algorithm converges very fast with the guidance of a priori target temporal and spatial distributions. Only one iteration is needed to reconstruct accurate optical absorption coefficient.

Citation Download Citation

Nanguang Chen, Puyun Guo, Shikui Yan, Daqing Piao, and Quing Zhu "Ultrasound-assisted NIR imaging for breast cancer detection", Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); https://doi.org/10.1117/12.434530

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
12 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Ultrasonography

Near infrared

Absorption

Transducers

Optical fibers

Optical properties

Sensors

Show All Keywords

Keywords/Phrases

Search In:

Publication Years