Paper
21 May 2001 Culture of bone-marrow-derived cells in microfabricated pit arrays
Hiroko E. Kikuchi, Yuji Kikuchi, Yoshinori Kuboki
Author Affiliations +
Abstract
Tissue cells cannot survive without the attachment to extracellular matrix (ECM). Furthermore, the geometry of ECM is known to play an essential role in the regulation for these cells to proliferate and differentiate so that tissues with normal morphologies can be formed or maintained. We have introduced microfabricated surface structures coated with ECM protein collagen into cell culture studies to examine a possibility of 3D patterning of ECM.
© (2001) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Hiroko E. Kikuchi, Yuji Kikuchi, and Yoshinori Kuboki "Culture of bone-marrow-derived cells in microfabricated pit arrays", Proc. SPIE 4265, Biomedical Instrumentation Based on Micro- and Nanotechnology, (21 May 2001); https://doi.org/10.1117/12.427973
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KEYWORDS
Microfabrication

Tissues

Bone

Collagen

Microscopy

Proteins

Silicon

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