0

Full Content is available to subscribers

Subscribe/Learn More  >
Proceedings Article

Principle of synchronous luminescence (SL) technique for biomedical diagnostics

[+] Author Affiliations
Tuan Vo-Dinh

Oak Ridge National Lab. (USA)

Proc. SPIE 3911, Biomedical Diagnostic, Guidance, and Surgical-Assist Systems II, 42 (May 3, 2000); doi:10.1117/12.384929
Text Size: A A A
From Conference Volume 3911

  • Biomedical Diagnostic, Guidance, and Surgical-Assist Systems II
  • Tuan Vo-Dinh; Warren S. Grundfest; David A. Benaron
  • San Jose, CA | January 22, 2000

abstract

In the present study, the principle of synchronous luminescence (SL) is described for use in biomedical diagnostics. The SL method involves scanning simultaneously both emission and excitation wavelengths while keeping a constant wavelength interval between them. This SF procedure simplifies the emission spectrum and provides for greater selectivity and is used to detect subtle differences in the fluorescence emission of the biochemical species of cells and tissues. The SL method can be used to analyze tissue in vivo or to investigate spectral differences in normal and neoplastic cells in vitro. SL scans of skin tissues illustrate the use of the method. For in vitro diagnostics, a difference between the flourescent spectra of the normal rat liver epithelial and hepatoma cell lines were detected using synchronous fluorescence. The potential use of SF as s screening tool for cancer diagnosis is discussed.

© (2000) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Tuan Vo-Dinh
"Principle of synchronous luminescence (SL) technique for biomedical diagnostics", Proc. SPIE 3911, Biomedical Diagnostic, Guidance, and Surgical-Assist Systems II, 42 (May 3, 2000); doi:10.1117/12.384929; http://dx.doi.org/10.1117/12.384929


Access This Article
Sign In to Access Full Content
Please Wait... Processing your request... Please Wait.
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
 

Figures

Tables

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

Advertisement


Buy this article ($18 for members, $25 for non-members).
Sign In