Optoacoustical tissue differentiation for on-line therapy control

Uwe Oberheide; Birte Jansen; Ingo Bruder; Holger Lubatschowski; Herbert Welling; Wolfgang Ertmer

doi:10.1117/12.409333

16 November 2000 Optoacoustical tissue differentiation for on-line therapy control

Uwe Oberheide, Birte Jansen, Ingo Bruder, Holger Lubatschowski, Herbert Welling, Wolfgang Ertmer

Proceedings Volume 4161, Optical Biopsy and Tissue Optics; (2000) https://doi.org/10.1117/12.409333
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

In this work, the localization of the ciliary body region of porcine eyes with laser optoacoustics was realized. The principle of laser optoacoustics combines the advantages of ultrasound and optical tomography. The absorption of short laser pulses in the near infrared generates thermoelastic stress waves in the ciliary muscle and the underlying pigmented epithelial layers. These stress transients were detected at the surface of the sclera with piezoelectric transducers in order to analyze the structure. The optoacoustical measurements of the ciliary body region at different positions from the corneoscleral limbus were composed to a grayscale image, which could be qualitatively compared to histological sections of this region. In these images the pigmented layers can be localized. The influence of the detectional wavelength on the optoacoustical signal in the NIR between 750 and 1052 nm was investigated. Furthermore, changes in the optoacoustic signal due to coagulation with a diode laser using typical therapeutical parameters could be observed.

Citation Download Citation

Uwe Oberheide, Birte Jansen, Ingo Bruder, Holger Lubatschowski, Herbert Welling, and Wolfgang Ertmer "Optoacoustical tissue differentiation for on-line therapy control", Proc. SPIE 4161, Optical Biopsy and Tissue Optics, (16 November 2000); https://doi.org/10.1117/12.409333

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