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Proceedings Article

Two-dimensional birefringence imaging in biological tissue using polarization-sensitive optical coherence tomography

[+] Author Affiliations
Johannes F. de Boer, Thomas E. Milner, J. Stuart Nelson

Univ. of California/Irvine (USA)

Martin J. C. van Gemert

Academic Medical Ctr. (Netherlands)

Proc. SPIE 3196, Optical and Imaging Techniques for Biomonitoring III, 32 (January 13, 1998); doi:10.1117/12.297943
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From Conference Volume 3196

  • Optical and Imaging Techniques for Biomonitoring III
  • Hans-Jochen Foth; Renato Marchesini; Halina Podbielska; Abraham Katzir
  • San Remo, Italy | September 04, 1997

abstract

Using a polarization sensitive Michelson interferometer, we measure 2D images of optical birefringence in bovine tendon as a function of depth with a technique known as optical coherence tomography (OCT). Detection of the polarization state of the signal, formed by interference of backscattered light from the sample and a mirror in the reference arm, gives the optical phase delay between light that has propagated along the fast and slow axes of the birefringent tendon. Images showing the change in birefringence in response to laser irradiation are presented. The technique allows rapid non-contact investigation of tissue structural properties through 2D imaging of birefringence.

© (1998) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Citation

Johannes F. de Boer ; Thomas E. Milner ; Martin J. C. van Gemert and J. Stuart Nelson
"Two-dimensional birefringence imaging in biological tissue using polarization-sensitive optical coherence tomography", Proc. SPIE 3196, Optical and Imaging Techniques for Biomonitoring III, 32 (January 13, 1998); doi:10.1117/12.297943; http://dx.doi.org/10.1117/12.297943


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