Cancer diagnosis by infrared spectroscopy: methodological aspects

Michael Jackson; Keith Kim; John Tetteh; James R. Mansfield; Brion Dolenko; Raymond L. Somorjai; F. William Orr; Peter H. Watson; Henry H. Mantsch

doi:10.1117/12.306098

24 April 1998 Cancer diagnosis by infrared spectroscopy: methodological aspects

Michael Jackson, Keith Kim, John Tetteh, James R. Mansfield, Brion Dolenko, Raymond L. Somorjai, F. William Orr, Peter H. Watson, Henry H. Mantsch

Author Affiliations +

Proceedings Volume 3257, Infrared Spectroscopy: New Tool in Medicine; (1998) https://doi.org/10.1117/12.306098
Event: BiOS '98 International Biomedical Optics Symposium, 1998, San Jose, CA, United States

Abstract

IR spectroscopy is proving to be a powerful tool for the study and diagnosis of cancer. The application of IR spectroscopy to the analysis of cultured tumor cells and grading of breast cancer sections is outlined. Potential sources of error in spectral interpretation due to variations in sample histology and artifacts associated with sample storage and preparation are discussed. The application of statistical techniques to assess differences between spectra and to non-subjectively classify spectra is demonstrated.

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Michael Jackson, Keith Kim, John Tetteh, James R. Mansfield, Brion Dolenko, Raymond L. Somorjai, F. William Orr, Peter H. Watson, and Henry H. Mantsch "Cancer diagnosis by infrared spectroscopy: methodological aspects", Proc. SPIE 3257, Infrared Spectroscopy: New Tool in Medicine, (24 April 1998); https://doi.org/10.1117/12.306098

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