Ho:YAG laser sclerostomy in a long-term animal model

Sandor G. Vari M.D.; Vani R. Pergadia; Wendy J. Snyder; Thanassis Papaioannou; William Fein; Michael C. Fishbein M.D.; Wei-Qiang Shi; M. D. Dhondt; Warren S. Grundfest M.D.

doi:10.1117/12.168720

15 February 1994 Ho:YAG laser sclerostomy in a long-term animal model

Sandor G. Vari M.D., Vani R. Pergadia, Wendy J. Snyder, Thanassis Papaioannou, William Fein, Michael C. Fishbein M.D., Wei-Qiang Shi, M. D. Dhondt, Warren S. Grundfest M.D.

Author Affiliations +

Proceedings Volume 2079, Laser Applications in Ophthalmology; (1994) https://doi.org/10.1117/12.168720
Event: Europto Biomedical Optics '93, 1993, Budapest, Hungary

Abstract

The effects of the Ho:YAG (2.13 micrometers ) laser on rabbit scleral tissue ablation were determined. Over a period of 12 months the status of the drain hole was monitored. A 3 mm incision was made on 26 rabbits through the conjunctiva and the laser probe was advanced and applied under it. A fluence of 255 J/cm² was used to perforate the sclera with a pulse duration of 300 microsecond(s) ec full width at half maximum. Results of this study show that this laser thermal sclerostomy procedure provided a patent hole in 6 of 8 (75%) eyes at 3 months, 11 of 15 (73%) eyes at 6 months, and 3 of 3 at 12 months. No postoperative inflammation, hypotony or subsequent scar formation was observed in any of the rabbits.

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Sandor G. Vari M.D., Vani R. Pergadia, Wendy J. Snyder, Thanassis Papaioannou, William Fein, Michael C. Fishbein M.D., Wei-Qiang Shi, M. D. Dhondt, and Warren S. Grundfest M.D. "Ho:YAG laser sclerostomy in a long-term animal model", Proc. SPIE 2079, Laser Applications in Ophthalmology, (15 February 1994); https://doi.org/10.1117/12.168720

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KEYWORDS

Patents

Inflammation

Eye models

Sclera

YAG lasers

Animal model studies

Eye

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