Ratio detection instrument of Kr+ laser-induced fluorescence for lung tumor

Qirong Lin; Shusen Xie; Buhong Li; Wei Zheng; Chuan-Zhao Zhou

doi:10.1117/12.330160

2 November 1998 Ratio detection instrument of Kr⁺ laser-induced fluorescence for lung tumor

Qirong Lin, Shusen Xie, Buhong Li, Wei Zheng, Chuan-Zhao Zhou

Proceedings Volume 3344, 1997 Shanghai International Conference on Laser Medicine and Surgery; (1998) https://doi.org/10.1117/12.330160
Event: 1997 Shanghai International Conference on Laser Medicine and Surgery, 1997, Shanghai, China

Abstract

The ratio detection of laser-fluorescence has become an important detection instrument of diagnosis and localization for lung tumor because its high sensitivity. But since it refers to the ratio judged by the reflective light from tissue surface in the previous work, it causes very high background noise and affects the stability of ratio detection. In this paper, we have performed experiments to study the variation regularity between the reflective light of tissue and autofluorescence of tissue and cause background noise of lung tissue in vitro. Based on the se experiments, we have developed the instrument of ratio detection which using the green autofluorescence instead of the reflective light of tissue for the ratio. The new system of ratio detection have the advantage of low background noise, thus it can effectively eliminate the false positive results for diagnosis and localization of lung tumor in clinic practice.

Citation Download Citation

Qirong Lin, Shusen Xie, Buhong Li, Wei Zheng, and Chuan-Zhao Zhou "Ratio detection instrument of Kr⁺ laser-induced fluorescence for lung tumor", Proc. SPIE 3344, 1997 Shanghai International Conference on Laser Medicine and Surgery, (2 November 1998); https://doi.org/10.1117/12.330160

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