Overview of a novel point of care instrument system for measuring whole blood Prothrombin time

Greg P. Carpenter; T. Gary Neel; James R. Parker

doi:10.1117/12.180788

21 July 1994 Overview of a novel point of care instrument system for measuring whole blood Prothrombin time

Greg P. Carpenter, T. Gary Neel, James R. Parker

Proceedings Volume 2136, Biochemical Diagnostic Instrumentation; (1994) https://doi.org/10.1117/12.180788
Event: OE/LASE '94, 1994, Los Angeles, CA, United States

Abstract

This paper describes a new diagnostic instrument which uses magnetic modulation of an optical signal to rapidly measure whole blood Prothrombin time. The new instrument improves diagnosing and level monitoring by allowing accurate, rapid, low cost near patient testing. The measurement system consists of five major components: a control system; a user interface, a disposable-strip laminate architecture with proprietary chemistry which interacts with a time-varying magnetic field and accelerates the coagulation reaction; an optical measurement module -- the optics assembly of the instrument contains a heater, electromagnet, dc magnet, and numerous reflective/transmissive radiometric sensor systems; and a calibration-instrument using a custom developed test device which accurately simulates the coagulation reaction's induced optical properties. The theory of operation of the coagulation assay system and optical measurement module is describe and typical data and performance metrics are presented. 6

Citation Download Citation

Greg P. Carpenter, T. Gary Neel, and James R. Parker "Overview of a novel point of care instrument system for measuring whole blood Prothrombin time", Proc. SPIE 2136, Biochemical Diagnostic Instrumentation, (21 July 1994); https://doi.org/10.1117/12.180788

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available