Multifrequency solid state YAG:Nd laser for diagnosis of malignant tumors

Asatur A. Lalayan; Lusine E. Aidinian; Hayro M. Galstian

doi:10.1117/12.323519

24 September 1998 Multifrequency solid state YAG:Nd laser for diagnosis of malignant tumors

Asatur A. Lalayan, Lusine E. Aidinian, Hayro M. Galstian

Proceedings Volume 3414, Opto-Contact: Workshop on Technology Transfers, Start-Up Opportunities,and Strategic Alliances; (1998) https://doi.org/10.1117/12.323519
Event: Lasers and Materials in Industry and Opto-Contact Workshop, 1998, Quebec, Canada

Abstract

The possibility of laser fluorescence diagnosis of malignant tumors with the aid of multifrequency (355, 440, 446, 532, 660, 670 nm) solid state YAG:Nd laser and the rise in accuracy of this method were discussed. Permitted for clinical employment sodium fluorescein has been used as human tumor-localizing dye. The fluorescence spectra of sodium fluorescein containing human normal tissue and breast, stomach, intestine, skin cancer during excitation with the third harmonics of YAG:Nd and with help of multichannel fiber-optic spectrofluorometer were studied. The contrast accumulation of the dye in tumors of different localization was investigated. The fluorescence spectra of chlorine e₆, containing animal tissues at different excitation wavelength (355, 532 and 660 nm) were obtained. The pharmacokinetic behavior of chlorine e₆, containing different organs and tumor tissues of rats, infected with Sarcoma-45 has been investigated.

Citation Download Citation

Asatur A. Lalayan, Lusine E. Aidinian, and Hayro M. Galstian "Multifrequency solid state YAG:Nd laser for diagnosis of malignant tumors", Proc. SPIE 3414, Opto-Contact: Workshop on Technology Transfers, Start-Up Opportunities,and Strategic Alliances, (24 September 1998); https://doi.org/10.1117/12.323519

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available