Asymmetry of light backscattering from Couette flow of RBC suspensions: application for biomonitoring of blood samples

Alexander V. Priezzhev; Stanislav G. Khatsevich; Vladimir V. Lopatin

doi:10.1117/12.339187

12 February 1999 Asymmetry of light backscattering from Couette flow of RBC suspensions: application for biomonitoring of blood samples

Alexander V. Priezzhev, Stanislav G. Khatsevich, Vladimir V. Lopatin

Author Affiliations +

Proceedings Volume 3567, Optical and Imaging Techniques for Biomonitoring IV; (1999) https://doi.org/10.1117/12.339187
Event: BiOS Europe '98, 1998, Stockholm, Sweden

Abstract

Asymmetry of light backscattering from a shear flow of 1 mm thick layer of whole blood was measured. The blood samples from different health and diseased individuals were placed in a gap of a cylindrical Couette cell with inner cylinder rotating with variable rates. Probing was performed with a CW He-Ne laser (633 nm). The difference in intensities of backscattered light detected through a transpatent wall of the stationary outer cylinder with a photodetector located at variable distances from the illuminating beam along and opposite to the flow directions depends on the distance between the illuminating and detecting probes, on shear rate, on hematocrit, and on the type of disease. The experiments conducted with blood samples from patients suffering from heart disease, bronchial asthma, and rheumatoid arthritis showed stable and reproducible difference in the amount of asymmetry. This makes the technique potentially applicable for optical biomonitoring and, also, for the study of rheology of concentrated suspensions of large deformable particles, like erythrocytes.

Citation Download Citation

Alexander V. Priezzhev, Stanislav G. Khatsevich, and Vladimir V. Lopatin "Asymmetry of light backscattering from Couette flow of RBC suspensions: application for biomonitoring of blood samples", Proc. SPIE 3567, Optical and Imaging Techniques for Biomonitoring IV, (12 February 1999); https://doi.org/10.1117/12.339187

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