Near-infrared time-resolved spectroscopy system for tissue oxygenation monitor

Motoki Oda; Yutaka Yamashita; Tetsuhisa Nakano; Akihiro Suzuki; Keiji Shimizu; Isuke Hirano; Fumihiko Shimomura; Etsuko Ohmae; Toshihiko Suzuki; Yutaka Tsuchiya

doi:10.1117/12.356809

15 July 1999 Near-infrared time-resolved spectroscopy system for tissue oxygenation monitor

Motoki Oda, Yutaka Yamashita, Tetsuhisa Nakano, Akihiro Suzuki, Keiji Shimizu, Isuke Hirano, Fumihiko Shimomura, Etsuko Ohmae, Toshihiko Suzuki, Yutaka Tsuchiya

Author Affiliations +

Proceedings Volume 3597, Optical Tomography and Spectroscopy of Tissue III; (1999) https://doi.org/10.1117/12.356809
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

We developed a three wavelength time-resolved spectroscopy system called the TRS-10 for use as a tissue oxygenation monitor. The TRS-10 achieved a higher data acquisition rate and a system miniaturization maintaining high sensitivity and time resolution. The TRS-10 consists of a three wavelength picosecond light pulser (PLP) with auto power control as a pulsed light source, a photomultiplier tube (PMT) having high speed and high sensitivity and miniaturized signal processing circuits for time-resolved measurement (CFD, TAC, A/D converter and histogram memory). The TRS-10 system was used to measure the time course of oxygen metabolism in a human forearm with a pneumatic cuff attached to occlude blood flow. Our system succeeded in accurately measuring concentrations of Oxy- (HbO2) and deoxyhemoglobin (Hb) in the human forearm based on diffusion theory by means of TRS data observation having an accumulation time of one second per point.

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Motoki Oda, Yutaka Yamashita, Tetsuhisa Nakano, Akihiro Suzuki, Keiji Shimizu, Isuke Hirano, Fumihiko Shimomura, Etsuko Ohmae, Toshihiko Suzuki, and Yutaka Tsuchiya "Near-infrared time-resolved spectroscopy system for tissue oxygenation monitor", Proc. SPIE 3597, Optical Tomography and Spectroscopy of Tissue III, (15 July 1999); https://doi.org/10.1117/12.356809

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