New concept of light dosimetry in photodynamic therapy: the control by using an ARX modeling

Laure Muller; Charles Abdul-Nour; Yves Granjon; Francois H. Guillemin; Edouard Yvroud

doi:10.1117/12.200814

31 January 1995 New concept of light dosimetry in photodynamic therapy: the control by using an ARX modeling

Laure Muller, Charles Abdul-Nour, Yves Granjon, Francois H. Guillemin, Edouard Yvroud

Proceedings Volume 2326, Photon Transport in Highly Scattering Tissue; (1995) https://doi.org/10.1117/12.200814
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

The control of light dosimetry during photodynamic therapy requires the knowledge of all the optical coefficient in situ. Therefore, a sensor based upon the backscattering phenomenon has been conceived. It is described in the first part. The second part of the paper shows how the combination of the Kubelka and Munk's theory and an ARX modeling of light gives access to the required values. In the last part the results obtained in vitro on optical phantoms and in vivo on nude mice are analyzed.

Citation Download Citation

Laure Muller, Charles Abdul-Nour, Yves Granjon, Francois H. Guillemin, and Edouard Yvroud "New concept of light dosimetry in photodynamic therapy: the control by using an ARX modeling", Proc. SPIE 2326, Photon Transport in Highly Scattering Tissue, (31 January 1995); https://doi.org/10.1117/12.200814

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