Numerical study of the feasibility of scanning hematoma and blood vessels in the human brain

Shechao Charles Feng; H.L. Zhao; Fanan Zeng

doi:10.1117/12.200862

31 January 1995 Numerical study of the feasibility of scanning hematoma and blood vessels in the human brain

Shechao Charles Feng, H.L. Zhao, Fanan Zeng

Proceedings Volume 2326, Photon Transport in Highly Scattering Tissue; (1995) https://doi.org/10.1117/12.200862
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

We study theoretically the problem of sensitivity of frequency modulated reflectance to the inclusion of either a hematoma, modeled as a large slab, or a blood vessel, modeled as a straight tube, in semi-infinite human tissue systems. We use two different numerical techniques: (1) numerical integration of three-dimensional diffusion equation; and (2) Monte Carlo simulations with a biasing technique. We find that inclusion of a hematoma slab or a blood vessel cylinder gives rise to significant change in both the phase and modulation as compared to a homogeneous medium. The reflected signals from these two situations are also significantly different which may allow differentiation between the two objects. In the particular case of imbedded cylindrical blood vessel we find that up to a depth of z equals 25 mm it is possible to use the phase shift or modulation change of reflected photon flux at different locations on the sample surface to determine the direction, size, and depth of the embedded blood vessel, provided phase change sensitivity of 0.1 deg or modulation change sensitivity 0.01 are available.

Citation Download Citation

Shechao Charles Feng, H.L. Zhao, and Fanan Zeng "Numerical study of the feasibility of scanning hematoma and blood vessels in the human brain", Proc. SPIE 2326, Photon Transport in Highly Scattering Tissue, (31 January 1995); https://doi.org/10.1117/12.200862

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available