Pulsed laser ablation of tissue: surface vaporization or thermal explosion?

Vasan Venugopalan

doi:10.1117/12.209881

22 May 1995 Pulsed laser ablation of tissue: surface vaporization or thermal explosion?

Vasan Venugopalan

Proceedings Volume 2391, Laser-Tissue Interaction VI; (1995) https://doi.org/10.1117/12.209881
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

In this paper we discuss the effects of laser-induced stresses and tissue chromophore targeting on the mechanism and dynamics of pulsed laser ablation. We argue that larger pulse durations and optical absorption coefficients reduce the contribution of photomechanical effects to the onset of material removal. Further we argue that if the structural integrity of the tissue extra-cellular matrix (ECM) is not compromised during irradiation, the ablation process will necessarily be explosive even if the heated tissue volume is allowed to mechanically equilibrate to the laser-induced stressed during irradiation. However, if the tissue is not inertially confined and the ECM is compromised during irradiation, the material removal is consistent with a process of rapid surface vaporization.

Citation Download Citation

Vasan Venugopalan "Pulsed laser ablation of tissue: surface vaporization or thermal explosion?", Proc. SPIE 2391, Laser-Tissue Interaction VI, (22 May 1995); https://doi.org/10.1117/12.209881

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