Microcirculation monitoring with real time spatial frequency domain imaging

Xinlin Chen; Zili Cao; Weihao Lin; Danfeng Zhu; Xiuwei Zhu; Bixin Zeng; M. Xu

doi:10.1117/12.2268805

5 January 2017 Microcirculation monitoring with real time spatial frequency domain imaging

Xinlin Chen, Zili Cao, Weihao Lin, Danfeng Zhu, Xiuwei Zhu, Bixin Zeng, M. Xu

Proceedings Volume 10245, International Conference on Innovative Optical Health Science; 102450J (2017) https://doi.org/10.1117/12.2268805
Event: International Conference on Innovative Optical Health Science, 2016, Shanghai Everbright International Hotel, China

Abstract

We present a spatial frequency domain imaging (SFDI) study of local hemodynamics in the forearm of healthy volunteers performing paced breathing. Real time Single Snapshot Multiple Frequency Demodulation - Spatial Frequency Domain Imaging (SSMD-SFDI) was used to map the optical properties of the subsurface of the forearm continuously. The oscillations of the concentrations of deoxy- and oxyhemoglobin at the subsurface of the forearm induced by paced breathing are found to be close to out-of-phase, attributed to the dominance of the blood flow modulation by paced breathing. The properties of local microcirculation including the blood transit times through capillaries and venules are extracted by fitting to Simplified Hemodynamics Model. Our preliminary results suggest that the real time SSMD-SFDI platform may serve as one effective imaging modality for microcirculation monitoring.

Citation Download Citation

Xinlin Chen, Zili Cao, Weihao Lin, Danfeng Zhu, Xiuwei Zhu, Bixin Zeng, and M. Xu "Microcirculation monitoring with real time spatial frequency domain imaging", Proc. SPIE 10245, International Conference on Innovative Optical Health Science, 102450J (5 January 2017); https://doi.org/10.1117/12.2268805

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available