Biomedical imaging by Talbot-type x-ray phase tomography

Atsushi Momose; Wataru Yashiro; Masafumi Moritake; Yoshihiro Takeda; Kentaro Uesugi; Akihisa Takeuchi; Yoshio Suzuki; Makoto Tanaka; Tadashi Hattori

doi:10.1117/12.678443

7 September 2006 Biomedical imaging by Talbot-type x-ray phase tomography

Atsushi Momose, Wataru Yashiro, Masafumi Moritake, Yoshihiro Takeda, Kentaro Uesugi, Akihisa Takeuchi, Yoshio Suzuki, Makoto Tanaka, Tadashi Hattori

Author Affiliations +

Proceedings Volume 6318, Developments in X-Ray Tomography V; 63180T (2006) https://doi.org/10.1117/12.678443
Event: SPIE Optics + Photonics, 2006, San Diego, California, United States

Abstract

An X-ray Talbot interferometer for X-ray phase imaging and tomography was constructed using an amplitude grating of a gold pattern 8 μm in pitch and 30 μm in height developed by X-ray lithography and gold electroplating. The effective area of the grating was 20 mm x 20 mm, and was fully illuminated by synchrotron radiation at beamline 20XU, SPring-8, Japan. Almost whole body of a fish 3 cm in length was observed by phase tomography. Resulting images obtained with 0.07 nm and 0.045 nm X-rays revealed organs with bones in the same view successfully. A preliminary result of the combination with an X-ray imaging microscope is also presented, which was attempted to attain a higher spatial resolution. Finally, prospects of the compatibility with a conventional X-ray generator are discussed for practical applications such as clinical diagnoses.

Citation Download Citation

Atsushi Momose, Wataru Yashiro, Masafumi Moritake, Yoshihiro Takeda, Kentaro Uesugi, Akihisa Takeuchi, Yoshio Suzuki, Makoto Tanaka, and Tadashi Hattori "Biomedical imaging by Talbot-type x-ray phase tomography", Proc. SPIE 6318, Developments in X-Ray Tomography V, 63180T (7 September 2006); https://doi.org/10.1117/12.678443

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