Integrated optic surface plasmon resonance measurements in glass substrates

A. Parisi; F. P. D'Aleo; S. Guarino; L. Curcio; G. Badalamenti; A. C. Cino; A. C. Busacca; E. D'Asaro; S. Riva Sanseverino

doi:10.1117/12.738629

2 July 2007 Integrated optic surface plasmon resonance measurements in glass substrates

A. Parisi, F. P. D'Aleo, S. Guarino, L. Curcio, G. Badalamenti, A. C. Cino, A. C. Busacca, E. D'Asaro, S. Riva Sanseverino

Author Affiliations +

Proceedings Volume 6619, Third European Workshop on Optical Fibre Sensors; 661926 (2007) https://doi.org/10.1117/12.738629
Event: Third European Workshop on Optical Fibre Sensors, 2007, Napoli, Italy

Abstract

The surface plasmon resonance (SPR) technique is an optical method that can be used to measure the refractive index of organic nano-layers adsorbed on a thin metal film. Although there are many techniques for measuring biomolecular interactions, SPR-based techniques play a central role in many current biosensing experiments, since they are most suited to sensitive and quantitative kinetic measurements. Here we give some results from the analysis and numerical elaboration of SPR data regarding the flow of different solutions with refractive indexes in the range of interest (1-1.4). After a brief discussion of the principles of SPR and of waveguide fabrication technique, we give a description of system setup and some results regarding the real time waveguide output intensity monitoring to measure the interaction between the gold thin film and the analyte.

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A. Parisi, F. P. D'Aleo, S. Guarino, L. Curcio, G. Badalamenti, A. C. Cino, A. C. Busacca, E. D'Asaro, and S. Riva Sanseverino "Integrated optic surface plasmon resonance measurements in glass substrates", Proc. SPIE 6619, Third European Workshop on Optical Fibre Sensors, 661926 (2 July 2007); https://doi.org/10.1117/12.738629

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