Prof. Sebastian Wachsmann-Hogiu Profile

Prof. Sebastian Wachsmann-Hogiu

Professor at McGill Univ

SPIE Involvement:

Conference Program Committee | Conference Chair | Editor | Author

Publications (30)

Proceedings Article | 13 March 2024 Presentation

On the dilemma of using small extracellular vesicles for label-free liquid biopsy

Sebastian Wachsmann-Hogiu

Proceedings Volume PC12858, PC1285803 (2024) https://doi.org/10.1117/12.3002716

KEYWORDS: Liquids, Biopsy, Biological samples, Pathology, Raman spectroscopy, Diseases and disorders, Chemical composition, Tissues, Surface enhanced Raman spectroscopy, Chemical analysis

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Proceedings Article | 13 March 2024 Presentation

On-chip chemiluminescence biosensor for detection of surface contamination

Meruyert Imanbekova, Reza Abbasi, Sebastian Wachsmann-Hogiu

Proceedings Volume PC12858, PC1285809 (2024) https://doi.org/10.1117/12.3009613

KEYWORDS: Chemiluminescence, Biosensors, Contamination, Acquisition tracking and pointing, Optical sensors, Solids, Sensor technology, Safety, Portability, Pathogens

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Proceedings Article | 13 March 2024 Presentation

Contact-mode fluorescence measurements on a lensless CMOS image sensor

Túlio Pedrosa, Renato Araujo, Sebastian Wachsmann-Hogiu

Proceedings Volume PC12858, PC1285804 (2024) https://doi.org/10.1117/12.3002784

KEYWORDS: Fluorescence, CMOS sensors, Biosensors, Tunable filters, Optical filters, Total internal reflection, Super resolution, Molecular interactions, Microscopy, Microscopes

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Proceedings Article | 13 March 2024 Presentation

SCOBY-derived, modified conductive nanocellulose with optical properties for nanoscale sensing

Xinyue Hu, Reza Abbasi, Meruyert Imanbekova, Mohul Sharma, Marion Vandewynckele-Bossut, Rupa Haldavnekar, Sebastian Wachsmann-Hogiu

Proceedings Volume PC12858, PC1285807 (2024) https://doi.org/10.1117/12.3008917

KEYWORDS: Electrical conductivity, Optical properties, Ultraviolet radiation, Biosensors, Yeast, Wound healing, Wearable devices, Surface enhanced Raman spectroscopy, Structured optical fibers, Raman scattering

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Proceedings Article | 17 March 2023 Presentation

Raman and SERS spectroscopy for EV characterization: detection of amyloid beta and bulk chemical analysis (Conference Presentation)

Meruyert Imanbekova, Tatu Rojalin, Silvia Hilt, Randy Carney, John Voss, Ayse Mine Saridag, Mehmet Kahraman, Humeyra Caglayan, Sebastian Wachsmann-Hogiu

Proceedings Volume PC12394, PC1239406 (2023) https://doi.org/10.1117/12.2656344

KEYWORDS: Raman spectroscopy, Surface enhanced Raman spectroscopy, Chemical analysis, Proteins, Molecular spectroscopy, Light scattering, Laser scattering, Imaging spectroscopy, Spectroscopy, Silver

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Proceedings Article | 17 March 2023 Presentation

Electrochemiluminescence detection of uric acid at point-of-need by using a lab-on-a-CMOS platform (Conference Presentation)

Reza Abbasi, Juanjuan Liu, Sorina Maria Suarasan, Sebastian Wachsmann-Hogiu

Proceedings Volume PC12394, PC1239403 (2023) https://doi.org/10.1117/12.2656342

KEYWORDS: Photons, Sensors, Photodetectors, Microscopes, Microfluidics, Digital recording, Diagnostics

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Proceedings Article | 5 March 2021 Presentation

Surface enhanced Raman scattering (SERS) nanoparticles for rapid chemical analysis of tumor-associated extracellular vesicles (EVs)

Randy Carney, Tatu Rojalin, Hanna Koster, Hannah O'Toole, Sebastian Wachsmann-Hogiu

Proceedings Volume 11659, 116590H (2021) https://doi.org/10.1117/12.2577297

KEYWORDS: Surface enhanced Raman spectroscopy, Tumors, Nanoparticles, Raman scattering, Chemical analysis, Cancer, Quartz, Proteins, Pathology, Neck

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Proceedings Article | 28 April 2020 Presentation

Raman spectroscopy for the analysis of exosomes (Conference Presentation)

Sebastian Wachsmann-Hogiu

Proceedings Volume 11243, 112431O (2020) https://doi.org/10.1117/12.2564934

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Proceedings Article | 10 March 2020 Presentation

Direct on-sensor imaging for shadow-based microparticle characterization and bioluminescence imaging (Conference Presentation)

Meruyert Imanbekova, Ayyappa Sudalaiyadum Perumal, Sara Kheireddine, Sebastian Wachsmann-Hogiu

Proceedings Volume 11254, 112540Y (2020) https://doi.org/10.1117/12.2550457

KEYWORDS: Bioluminescence, Sensors, Bacteria, Cameras, Spatial resolution, Imaging systems, Image resolution, CMOS sensors, Liquids, Infrared sensors

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Proceedings Article | 13 March 2019 Presentation

High spatial resolution and large field of view mobile phone-based microscopy with adaptive phone screen illumination (Conference Presentation)

Sara Kheireddine, Ayyappasamy Sudalaiyadum Perumal, Dan Nicolau, Sebastian Wachsmann-Hogiu

Proceedings Volume 10881, 108810M (2019) https://doi.org/10.1117/12.2510106

KEYWORDS: Spatial resolution, Cell phones, Microscopy, Microorganisms, Microfluidics, Imaging systems, Image resolution, Visualization, Image sensors, Cameras

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Proceedings Article | 4 March 2019 Presentation

Biosilica-Ag nanocomposites on adhesive tapes for low-cost flexible SERS substrates (Conference Presentation)

Mehmet Kahraman, Aysun Korkmaz, Maya Kenton, Gulsen Aksin, Sebastian Wachsmann-Hogiu, Juanjuan Liu

Proceedings Volume 10891, 108910F (2019) https://doi.org/10.1117/12.2508898

KEYWORDS: Surface enhanced Raman spectroscopy, Nanocomposites, Adhesives, Signal detection, Nanoparticles, Raman spectroscopy, Nanostructures, Biosensors, Bacteria, Proteins

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Proceedings Article | 4 March 2019 Presentation

A flexible and portable nanocomposite-based substrate for electrochemical biosensing (Conference Presentation)

Juanjuan Liu, Ayyappasamy Perumal, François Doucet, Kheiredine Rifai, Lütfü Özcan, Sara Kheireddine, Dan Nicolau, Sebastian Wachsmann-Hogiu

Proceedings Volume 10891, 108910E (2019) https://doi.org/10.1117/12.2508820

KEYWORDS: Biosensing, Nanoparticles, Carbon, Urea, Proteins, Electrodes, Silver, Biosensors, Molecules, Metals

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Proceedings Article | 19 February 2018 Presentation + Paper

Thermo-mechanical mechanism of laser-assisted alteration and stabilization of micro pore structure in eye-sclera

Olga Baum, Sebastian Wachsmann-Hogiu, Emil Sobol

Proceedings Volume 10496, 1049617 (2018) https://doi.org/10.1117/12.2289885

KEYWORDS: Laser stabilization, Sclera, Gas lasers, Laser tissue interaction, Microscopy, Collagen, Radiation effects, Eye, Super resolution, Atomic force microscopy

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SPIE Journal Paper | 31 May 2017 Open Access

Laser-induced micropore formation and modification of cartilage structure in osteoarthritis healing

Emil Sobol, Olga Baum, Anatoly Shekhter, Sebastian Wachsmann-Hogiu, Alexander Shnirelman, Yulia Alexandrovskaya, Ivan Sadovskyy, Valerii Vinokur

JBO, Vol. 22, Issue 09, 091515, (May 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.9.091515

KEYWORDS: Cartilage, Laser therapeutics, Tissues, In vivo imaging, Biopolymers

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Proceedings Article | 3 April 2017 Paper

Time-resolved SERS for characterizing extracellular vesicles

Tatu Rojalin, Heikki Saari, Petter Somersalo, Saara Laitinen, Mikko Turunen, Tapani Viitala, Sebastian Wachsmann-Hogiu, Zachary Smith, Marjo Yliperttula

Proceedings Volume 10080, 100800U (2017) https://doi.org/10.1117/12.2271865

KEYWORDS: Surface enhanced Raman spectroscopy, Raman spectroscopy, Data analysis, Blood, Polymers, Spectroscopy, Principal component analysis, Pharmacy, Precision mechanics, Nanoparticles

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Proceedings Article | 3 May 2016 Presentation

Raman spectroscopy of single extracellular vesicles reveals subpopulations with varying membrane content (Conference Presentation)

Zachary Smith, Changwon Lee, Tatu Rojalin, Randy Carney, Sidhartha Hazari, Alisha Knudson, Kit Lam, Heikki Saari, Elisa Lazaro Ibañez, Tapani Viitala, Timo Laaksonen, Marjo Yliperttula, Sebastian Wachsmann-Hogiu

Proceedings Volume 9704, 97040Q (2016) https://doi.org/10.1117/12.2212914

KEYWORDS: Raman spectroscopy, Proteins, Cancer, Chemical analysis, Biomedical optics, Laser spectroscopy, Principal component analysis, Industrial chemicals, Spectroscopy, Medical research

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Proceedings Article | 27 April 2016 Presentation

Smart fast blood counting of trace volumes of body fluids from various mammalian species using a compact custom-built microscope cytometer (Conference Presentation)

Zachary Smith, Tingjuan Gao, Tzu-Yin Lin, Danielle Carrade-Holt, Stephen Lane, Dennis Matthews, Denis Dwyre, Sebastian Wachsmann-Hogiu

Proceedings Volume 9715, 97150J (2016) https://doi.org/10.1117/12.2212881

KEYWORDS: Blood, Microfluidics, Microscopes, Biomedical optics, Diagnostics, Flow cytometry, Statistical analysis, Optical diagnostics, Optical sensing, Point-of-care devices

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Proceedings Article | 27 April 2016 Presentation

Combined fiber probe for fluorescence lifetime and Raman spectroscopy (Conference Presentation)

Sebastian Dochow, Dinglong Ma, Ines Latka, Thomas Bocklitz, Brad Hartl, Julien Bec, Hussain Fatakdawala, Sebastian Wachsmann-Hogiu, Eric Marple, Kirk Urmey, Michael Schmitt, Laura Marcu, Jürgen Popp

Proceedings Volume 9698, 969806 (2016) https://doi.org/10.1117/12.2214151

KEYWORDS: Raman spectroscopy, Luminescence, In vivo imaging, Tissues, Biomedical optics, Raster graphics, Diagnostics, Biological research, Spectroscopy, Fiber optics

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Proceedings Article | 22 April 2016 Paper

Plasmonic nanostructures for bioanalytical applications of SERS

Mehmet Kahraman, Sebastian Wachsmann-Hogiu

Proceedings Volume 9724, 972405 (2016) https://doi.org/10.1117/12.2214069

KEYWORDS: Surface enhanced Raman spectroscopy, Nanostructures, Plasmonics, Proteins, Nanolithography, Latex, Particles, Raman scattering, Biological research, Chemical analysis, Silver, Raman spectroscopy, Scanning electron microscopy

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SPIE Journal Paper | 1 July 2010 Open Access

Direct detection of aptamer-thrombin binding via surface-enhanced Raman spectroscopy

Cynthia Pagba, Stephen Lane, Hansang Cho, Sebastian Wachsmann-Hogiu

JBO, Vol. 15, Issue 04, 047006, (July 2010) https://doi.org/10.1117/12.10.1117/1.3465594

KEYWORDS: Surface enhanced Raman spectroscopy, Molecules, Nanoparticles, Proteins, Raman spectroscopy, Metals, Receptors, Silver, Raman scattering, Target detection

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Proceedings Article | 19 February 2007 Paper

Wide-field two-photon microscopy: features and advantages for biomedical applications

S. Wachsmann-Hogiu, J. Hwang, E. Lindsley, D. Farkas

Proceedings Volume 6441, 64411B (2007) https://doi.org/10.1117/12.711603

KEYWORDS: Luminescence, Confocal microscopy, Objectives, Tissues, Fluorescence lifetime imaging, Picosecond phenomena, Biomedical optics, Microscopy, Blood, Two photon excitation microscopy

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Proceedings Article | 19 February 2007 Paper

Multimode optical imaging of small animals: development and applications

J. Y. Hwang, C. Moffatt-Blue, O. Equils, M. Fujita, J. Jeong, N. Khazenzon, E. Lindsley, J. Ljubimova, A. Nowatzyk, D. Farkas, S. Wachsmann-Hogiu

Proceedings Volume 6441, 644105 (2007) https://doi.org/10.1117/12.711582

KEYWORDS: Imaging systems, Luminescence, Tumors, Tissues, Bioluminescence, Fluorescence lifetime imaging, Optical imaging, Hyperspectral imaging, Breast, Charge-coupled devices

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Proceedings Article | 22 February 2006 Paper

Spectral imaging detects breast cancer in fresh unstained specimens

Alice Chung, Mark Gaon, Jihoon Jeong, Scott Karlan, Erik Lindsley, Sebastian Wachsmann-Hogiu, Yizhi Xiong, Tong Zhao, Daniel Farkas

Proceedings Volume 6088, 608806 (2006) https://doi.org/10.1117/12.644927

KEYWORDS: Tissues, Breast cancer, Imaging spectroscopy, Image segmentation, Breast, Cancer, Tumors, Image classification, In vivo imaging, Library classification systems

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Proceedings Article | 29 March 2005 Paper

Multiphoton, confocal, and lifetime microscopy for molecular imaging in cartilage

Sebastian Wachsmann-Hogiu, Deborah Krakow, Veneta Kirilova, Daniel Cohn, Cristina Bertolotto, Dora Acuna, Qiyin Fang, Nikola Krivorov, Daniel Farkas

Proceedings Volume 5699, (2005) https://doi.org/10.1117/12.597670

KEYWORDS: Confocal microscopy, Luminescence, Fluorescence resonance energy transfer, Cartilage, Proteins, Fluorescence lifetime imaging, Multiphoton microscopy, Tissues, Microscopy, Molecular imaging

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Proceedings Article | 1 July 2004 Paper

Confocal and two-photon imaging in cartilage: expression patterns of Filamin A and B

Sebastian Wachsmann-Hogiu, Deborah Krakow, Eiman Sebald, Cristina Bertolotto, Dora Acuna, Daniel Farkas

Proceedings Volume 5322, (2004) https://doi.org/10.1117/12.561883

KEYWORDS: Confocal microscopy, Cartilage, Tissues, Luminescence, Proteins, Two photon imaging, Laser scanners, Objectives, Microscopy, Digital image correlation

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Proceedings Article | 12 March 2001 Paper

Stimulated Raman scattering in compressed gases by short laser pulses

Alexander Vodchits, Wolfgang Werncke, S. Hogiu, Valentin Orlovich

Proceedings Volume 4352, (2001) https://doi.org/10.1117/12.418810

KEYWORDS: Raman spectroscopy, Methane, Hydrogen, Picosecond phenomena, Gases, Prisms, Raman scattering, Femtosecond phenomena, Laser scattering, Dye lasers

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Proceedings Article | 5 December 1996 Paper

Preliminary studies of rabbit corneal structure using laser beams

Benone Carstocea, Otilia Gafencu, Silvia Apostol, Marcel Ionita, Mihail-Lucian Pascu, N. Moise, Gheorghe Popescu, Miruna Roman, S. Hogiu

Proceedings Volume 2930, (1996) https://doi.org/10.1117/12.260882

KEYWORDS: Cornea, Eye, Reflection, Microscopes, Confocal microscopy, Helium neon lasers, Refractive index, Geometrical optics, Collimation, Laser development

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Proceedings Article | 15 January 1996 Paper

Laser-induced fluorescence studies on collagen, cholesterol, and chlorophyll a

Mihail-Lucian Pascu, N. Moise, S. Hogiu

Proceedings Volume 2630, (1996) https://doi.org/10.1117/12.230035

KEYWORDS: Luminescence, Laser induced fluorescence, Collagen, Bioalcohols, Optical fibers, Curium, Nanolithography, Cardiovascular system, Laser applications, Liquids

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Proceedings Article | 27 December 1995 Paper

Laser-induced fluorescence studies on collagen, cholesterol, and chlorophyll a

Mihail-Lucian Pascu, N. Moise, S. Hogiu

Proceedings Volume 2627, (1995) https://doi.org/10.1117/12.228895

KEYWORDS: Luminescence, Laser induced fluorescence, Collagen, Bioalcohols, Optical fibers, Curium, Cardiovascular system, Nanolithography, Laser applications, Liquids

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Proceedings Article | 8 March 1995 Paper

Study of chlorophyll a (in vitro) flourescence induced by nitrogen-pulsed laser radiation

S. Hogiu, Mihail-Lucian Pascu, Laura Tugulea

Proceedings Volume 2461, (1995) https://doi.org/10.1117/12.203569

KEYWORDS: Luminescence, Pulsed laser operation, Molecules, In vitro testing, Photons, Nitrogen, Laser induced fluorescence, Bioalcohols, Absorption, Spectroscopy

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Showing 5 of 30 publications

Proceedings Volume Editor (5)

SPIE Conference Volume | 29 March 2024

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI

SPIE Conference Volume | 2 May 2023

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XX

SPIE Conference Volume | 14 April 2022

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIX

SPIE Conference Volume | 13 April 2021

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVIII

SPIE Conference Volume | 4 March 2020

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII

Conference Committee Involvement (34)

Optics and Biophotonics in Low-Resource Settings XI

25 January 2025 | San Francisco, California, United States

Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXIII

25 January 2025 | San Francisco, California, United States

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXII

25 January 2025 | San Francisco, California, United States

Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXII

29 January 2024 | San Francisco, California, United States

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI

28 January 2024 | San Francisco, California, United States

Optics and Biophotonics in Low-Resource Settings X

27 January 2024 | San Francisco, California, United States

Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXI

30 January 2023 | San Francisco, California, United States

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XX

30 January 2023 | San Francisco, California, United States

Optics and Biophotonics in Low-Resource Settings IX

28 January 2023 | San Francisco, California, United States

Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XX

24 January 2022 | San Francisco, California, United States

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIX

24 January 2022 | San Francisco, California, United States

Optics and Biophotonics in Low-Resource Settings VIII

22 January 2022 | San Francisco, California, United States

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVIII

6 March 2021 | Online Only, California, United States

Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIX

6 March 2021 | Online Only, California, United States

Optics and Biophotonics in Low-Resource Settings VII

6 March 2021 | Online Only, California, United States

Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVIII

3 February 2020 | San Francisco, California, United States

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII

2 February 2020 | San Francisco, California, United States

Optics and Biophotonics in Low-Resource Settings VI

1 February 2020 | San Francisco, California, United States

Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVII

4 February 2019 | San Francisco, California, United States

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVI

3 February 2019 | San Francisco, California, United States

Optics and Biophotonics in Low-Resource Settings V

2 February 2019 | San Francisco, California, United States

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XV

30 January 2018 | San Francisco, California, United States

Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVI

29 January 2018 | San Francisco, California, United States

Optics and Biophotonics in Low-Resource Settings IV

27 January 2018 | San Francisco, California, United States

Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIV

30 January 2017 | San Francisco, California, United States

Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XV

30 January 2017 | San Francisco, California, United States

Optics and Biophotonics in Low-Resource Settings III

28 January 2017 | San Francisco, California, United States

Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues IX

15 February 2016 | San Francisco, California, United States

Optics and Biophotonics in Low-Resource Settings II

13 February 2016 | San Francisco, California, United States

Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIII

9 February 2015 | San Francisco, California, United States

Optics and Biophotonics in Low-Resource Settings

7 February 2015 | San Francisco, California, United States

Optical Biopsy XII

4 February 2014 | San Francisco, California, United States

Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XII

3 February 2014 | San Francisco, California, United States

Optical Biopsy XI

5 February 2013 | San Francisco, California, United States

Showing 5 of 34 Conference Committees

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