Prof. Sukho Park Profile

Prof. Sukho Park

at Chonnam National Univ

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 24 October 2012 Paper

Development of intelligent theragonostic bacteria-based biomedical microrobot

Sungjun Park, Seong Young Ko, Jong-Oh Park, Sukho Park

Proceedings Volume 8548, 85486E (2012) https://doi.org/10.1117/12.981717

KEYWORDS: Bacteria, Picosecond phenomena, Optical lithography, Plasma, Microfluidics, Oxygen, Biomedical optics, Coating, Ultraviolet radiation, Reactive ion etching

Read Abstract +

We proposed new concepts on the development of intelligent biomedical microrobot using flagellated bacteria Salmonella typhimurium which has various properties such as micro-actuators, micro-sensors, treatment and diagnosis of solid tumors. We fabricated a bacteria-based microrobot using attenuated Salmonella typhimurium for medical applications. In addition, for motility enhancement of microrobots, we regulated the bacteria selective attachment on microbead surfaces using the patterning methods through the submerged property of microbeads on agarose gel. Firstly, we fabricated bacteria-based microrobots using polystyrene (PS) microbeads which are treated with anti-bacterial adherent factors, such as O2 plasma or bovine serum albumin. The selective bacteria-attached PS microbead groups using O2 plasma or BSA are showed higher motility than untreated whole bacteria-attached PS microbead groups. Secondly, we fabricated bacteria-based microrobots using biocompatible materials, poly(ethylene glycol) (PEG). We regulate the bacteria selective attachment on PEG microbead surfaces using bacteria adhesion materials, poly-L-lysine (PLL). Similar with the bacteria-based microrobots using PS microbeads, the selective bacteria-attached PEG microbeads group through the PLL selective coating showed higher motility than PLL-uncoated and whole PLL-coated PEG microbeads groups. Therefore, we expected that the proposed fabrication methods of the bacteria-based microrobots could have the following characteristics such as the high efficiency using flagellated bacteria, the enhanced motility using the bacteria selective patterning, and the potential applicability to human body using the biocompatible materials.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years