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13 March 2024 Second generation Powell lens line-field OCT for in-vivo, contactless, volumetric imaging of the cellular structure of the human cornea
Keyu Chen, Nima Abbasi, Alexander Wong, Kostadinka Bizheva
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Proceedings Volume PC12824, Ophthalmic Technologies XXXIV; PC128240V (2024) https://doi.org/10.1117/12.3005735
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
The optical design of a second generation Powell Lens-based Line-Field OCT system is presented. The new design offers improved FOV, DOF and sensitivity to allow for contactless, volumetric in-vivo imaging of the human cornea. Images acquired from healthy subjects reveal the cellular structure of the corneal epithelial and endothelial layers, sub-basal and stromal nerves. The high axial resolution allows for both visualization and morphometry of the thin corneal nerves such as the endothelium, Descemet’s membrane and pre-Descemet’s (Dua) layer. Visualization of endothelial nuclei allows for fast and easy counting of endothelial cells.
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Keyu Chen, Nima Abbasi, Alexander Wong, and Kostadinka Bizheva "Second generation Powell lens line-field OCT for in-vivo, contactless, volumetric imaging of the cellular structure of the human cornea", Proc. SPIE PC12824, Ophthalmic Technologies XXXIV, PC128240V (13 March 2024); https://doi.org/10.1117/12.3005735
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KEYWORDS
Cornea
Corneal imaging
In vivo imaging
Optical coherence tomography
Imaging systems
Visualization
Eye
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