Multi-beam optical coherence tomography for microvascular imaging of human skin in vivo

Chaoliang Chen; Kyle H. Y. Cheng; Raphael Jakubovic; Jamil Jivraj; Joel Ramjist; Ryan Deorajh; Wanrong Gao; Victor X. D. Yang

doi:10.1117/12.2250739

17 February 2017 Multi-beam optical coherence tomography for microvascular imaging of human skin in vivo

Chaoliang Chen, Kyle H. Y. Cheng, Raphael Jakubovic, Jamil Jivraj, Joel Ramjist, Ryan Deorajh, Wanrong Gao, Victor X. D. Yang

Author Affiliations +

Proceedings Volume 10070, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXIV; 1007017 (2017) https://doi.org/10.1117/12.2250739
Event: SPIE BiOS, 2017, San Francisco, California, United States

Abstract

In this paper, a multi-beam optical coherence tomography (OCT) was used to reconstruct the microvascular image of human skin in vivo with phase resolved Doppler OCT (PRDOCT), phase resolved Doppler variance (PRDV) and speckle variance OCT (svOCT), in which the blood flow image was calculated by averaging the four blood flow images obtained by the four beams. In PRDOCT method, it is difficult to detect the blood flow perpendicular to optical axis of the probe beam for single beam OCT, but the multi-beam scanning method can solve this because the input angles of the four probe beams are slightly different from each other. The proposed method can further improve the signal-to-noise ratio (SNR) of the blood flow signals extracted by the three methods mentioned above.

Citation Download Citation

Chaoliang Chen, Kyle H. Y. Cheng, Raphael Jakubovic, Jamil Jivraj, Joel Ramjist, Ryan Deorajh, Wanrong Gao, and Victor X. D. Yang "Multi-beam optical coherence tomography for microvascular imaging of human skin in vivo", Proc. SPIE 10070, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXIV, 1007017 (17 February 2017); https://doi.org/10.1117/12.2250739

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