Resonance Raman and fluorescence spectroscopy to evaluate increased brain kynurenine pathway activity in samples from patients with neurodegenerative disease

Laura A. Sordillo; Lin Zhang; Lingyan Shi; Vidyasagar Sriramoju; Peter P. Sordillo; Robert R. Alfano

doi:10.1117/12.2317118

24 April 2018 Resonance Raman and fluorescence spectroscopy to evaluate increased brain kynurenine pathway activity in samples from patients with neurodegenerative disease

Laura A. Sordillo, Lin Zhang, Lingyan Shi, Vidyasagar Sriramoju, Peter P. Sordillo, Robert R. Alfano

Author Affiliations +

Proceedings Volume 10711, Biomedical Imaging and Sensing Conference; 107111F (2018) https://doi.org/10.1117/12.2317118
Event: SPIE Structured Light, 2018, Yokohama, Japan

Abstract

Resonance Raman and fluorescence spectroscopy were used to assess increased kynurenine pathway activity in brain samples from Alzheimer’s patients and age-matched controls. Increased activity was seen in areas of the brain involved in Alzheimer’s disease.

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Laura A. Sordillo, Lin Zhang, Lingyan Shi, Vidyasagar Sriramoju, Peter P. Sordillo, and Robert R. Alfano "Resonance Raman and fluorescence spectroscopy to evaluate increased brain kynurenine pathway activity in samples from patients with neurodegenerative disease", Proc. SPIE 10711, Biomedical Imaging and Sensing Conference, 107111F (24 April 2018); https://doi.org/10.1117/12.2317118

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